Research
Current focus, framework, and outputs.
The active design work, the framework that supports it, and the publications produced as part of it.
Current focus
Noviota’s active research is the design of programmable cellular systems for infectious disease intervention. The work concentrates on the design and documentation layer that sits upstream of experimental validation, manufacturing and clinical translation.
Specifically: developing extensions to SBOL3 for the demands of nanomedicine, building reference implementations of the Nanomedicine Design Stack, and assembling case studies that demonstrate the framework against lipid nanoparticle therapeutic candidates.
The Nanomedicine Design Stack
The Nanomedicine Design Stack is Noviota’s framework for standardised biological design representation. It is a layered specification for describing nanomedicine systems in machine-readable form, addressing reproducibility, regulatory translation and computational learning requirements that current documentation practices do not adequately support.
The framework draws on SBOL3 as its foundation and extends it across the representational requirements of lipid nanoparticle therapeutics, programmable cellular systems, and the data infrastructure necessary to make such designs auditable across their development lifecycle.
Publications and outputs
A formal white paper on the Nanomedicine Design Stack is available on request. A public version is in preparation. Further outputs, including reference implementations and worked case studies, will be published as they reach the stage of release.